In vitro Antioxidant Activity of Lectin from Different Endophytic Fungi of Viscum album L.

In vitro and in vivo antidiabetic activity of lectin (N-acetyl- galactosamine, 64 kDa) isolated from endophytic fungi, Alternaria species from Viscum album on alloxan induced diabetic rats

Viscum album and its endophytic fungal species lectin are reported as antioxidant, antimicrobial, anti-inflammatory and anticancer activity. The present investigation was undertaken to in vitro (by enzymes inhibition) and in vivo antidiabetic activity of endopytic fungi, Alternaria species N-acetyl-galactosamine, 54 kDa protein lectin in alloxan induced diabetes in rats. Endophytic fungal lecti...

Antioxidant Activity of European Mistletoe (Viscum album)

Lectin from Viscum album L. inhibits protein synthesis in a lysate of rabbit reticulocytes

Mistletoe has been used as a drug against different diseases in po­ pular medicine for a long time, but the systematic research into anti-neoplastic activity of mistletoe extracts started only recently. Biological and anti-tumor activity of many protein fractions from mistletoe ex­ tract has been thouroughly investigated by V e s t e r et al. (1968 a, b), who determined optimal conditions for t...

Inhibition of protein synthesis by a toxic lectin from Viscum album L. (mistletoe).

1. The haemagglutinating and toxic lectin from Viscum album L. (mistletoe) inhibits protein synthesis in a lysate of rabbit reticulocytes, with an ID50 (concentration giving 50% inhibition) of 2.6 microgram/ml. This effect is enhanced (ID50 0.21 microgram/ml) if the lectin is reduced with 2-mercaptoethanol. 2. The lectin inhibits protein synthesis also in BL8L cells in culture. Inhibition occur...

NMR structural determination of viscotoxin A3 from Viscum album L.

The high-resolution three-dimensional structure of the plant toxin viscotoxin A3, from Viscum album L., has been determined in solution by (1)H NMR spectroscopy at pH 3.6 and 12 degrees C (the structure has been deposited in the Protein Data Bank under the id. code 1ED0). Experimentally derived restraints including 734 interproton distances from nuclear Overhauser effect measurements, 22 hydrog...